TA504328 CYP2B6 antibody

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0.1 ml / €379.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Canine, Human, Monkey, Mouse, Rat CYP2B6 OTI3D5

TA504328

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Product Description for CYP2B6

Mouse anti Canine, Human, Monkey, Mouse, Rat CYP2B6 OTI3D5.
Presentation: Purified
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for CYP2B6

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 IIB1
Presentation Purified
Reactivity Can, Hu, Mky, Ms, Rt
Applications F, ICC/IF, P, WB
Clonality Monoclonal
Clone OTI3D5
Host Mouse
Isotype IgG2a
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P20813
Immunogen:
Full length human recombinant protein of human CYP2B6(NP_000758) produced in HEK293T cell.
GeneID:
1555
Isotype control AM03096PU-N
Application WB 1:500~2000
IHC 1:150
IF 1:100
FLOW 1:100
Background This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygeses which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008].
Product Citations
Originator or purchased from resellers:
  1. Sim J, Nam W, Lee D, Lee S, O H, Joo J, et al. Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer. Arch Pharm Res. 2015 May;38(5):725-33. doi: 10.1007/s12272-014-0443-0. Epub 2014 Jul 23. PubMed PMID: 25052955.
  2. Chai J, Feng X, Zhang L, Chen S, Cheng Y, He X, et al. Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstruction. PLoS One. 2015 Mar 23;10(3):e0120055. doi: 10.1371/journal.pone.0120055. eCollection 2015. PubMed PMID: 25798860. (Free PMC Article available)
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for CYP2B6 (3 products)

Catalog No. Species Pres. Purity   Source  

CYP2B6

CYP2B6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CYP2B6

CYP2B6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CYP2B6

CYP2B6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for CYP2B6 (1 products)

Catalog No. Species Pres. Purity   Source  

CYP2B6 overexpression lysate

CYP2B6 overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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