discontinued

SP4110P Cysteinyl Leukotriene Receptor 2 (CysLT2) antibody

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50 µg / €470.00

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Rabbit anti Human Cysteinyl Leukotriene Receptor 2 (CysLT2)

SP4110P

Product Description for Cysteinyl Leukotriene Receptor 2 (CysLT2)

Rabbit anti Human Cysteinyl Leukotriene Receptor 2 (CysLT2).
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for Cysteinyl Leukotriene Receptor 2 (CysLT2)

Product Category Primary Antibodies
Quantity 50 µg
Synonyms AB13174
Presentation Aff - Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide - KLH conjugated
Epitope: 2nd extracellular domain of human
Remarks:
The immunizing peptide shows 47 % identity (47 % similarity) with rat.
Application Immunohistochemistry with formalin fixed paraffin embedded tissues: 4-36 µg/ml
Antigen retrieval:
Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Background Cysteinyl leukotriene receptor 2 (CysLT2) is a Chemoattractant Receptor that binds neutrophil chemoattractants such as cysteinyl leukotrienes. These ligands have potent proinflammatory activity and are implicated in many features of asthma including edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Activation of cysteinyl leukotriene receptor 2 induces cell contraction and/or relaxation.
CysLT2 expression has been reported in adrenal medulla, blood, brain, heart, kidney, lung, lymph node, ovary, placenta, prostate, pulmonary artery and vein, small intestine, and spleen. ESTs have been isolated from human kidney and liver/spleen libraries.
Concentration 1.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Peptide immunogen affinity column
Buffer System:
PBS, pH 7.7, containing 0.01% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Specificity
Specificity:
Reacts with Cysteinyl Leukotriene Receptor 2 (family: GPCR; subfamily: Chemoattractant).
Species:
Human.

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