BP5076 Cytokeratin 13 antibody

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0.1 ml / €380.00
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Guinea Pig anti Human, Mouse Cytokeratin 13

BP5076

Product Description for Cytokeratin 13

Guinea Pig anti Human, Mouse Cytokeratin 13.
Presentation: Serum
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Properties for Cytokeratin 13

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13
Presentation Serum
Reactivity Hu, Ms
Applications C, ICC/IF, P, WB
Clonality Polyclonal
Host Guinea Pig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P13646
Immunogen:
Synthetic peptide (TTTSSASVTTTSNA-C) of Human keratin K13 (formerly also designated cytokeratin 13), coupled to KLH.
GeneID:
3860
Application Immunoblotting: 1/3000 (ECL method).
Immunohistochemistry on Frozen Sections:
1/200.
Immunohistochemistry on Paraffin Sections:
1/100 (after microwave treatment).
Immunohistochemistry on Cytological Material.
Positive Control:
Squamous epithelium of esophagus, gingival, palate, vagina (staining all of the suprabasal layers).
Incubation Time:
1h at RT, extended with Paraffin Sections.
Background Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
Product Citations
Purchased from Acris:
  1. Castillo D, Seidel K, Salcedo E, Ahn C, de Sauvage FJ, Klein OD, et al. Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development. 2014 Aug;141(15):2993-3002. doi: 10.1242/dev.107631. Epub 2014 Jul 3. PubMed PMID: 24993944. (Free PMC Article available)
General Readings
  1. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell. 1982 Nov;31(1):11-24. PubMed PMID: 6186379.
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Preservatives:
0.09% Sodium Azide
Stabilizers:
0.5% BSA
State:
Stabilized Liquid antiserum
Serum
Species Reactivity
Species reactivity (tested):
Human, Mouse.
Specificity
Specificity:
This antibody recognizes Acidic Human keratin K13 (Mr 55 000).
Excellent marker to discriminate non-cornified squamous epithelia (esophagus, vagina, gingival) from those of different origin. Negative on foot sole, scalp.
Tumors Specifically Detected: Several squamous cell carcinomas, e.g. cervix carcinoma; transitional cell carcinoma of the bladder; craniopharyngioma.
Gene ID 3860
FocusOn and Reviews
Reviews:

Accessory Products

Proteins and/or Positive Controls

Proteins for Cytokeratin 13 (2 products)

Catalog No. Species Pres. Purity   Source  

Cytokeratin 13 (full length, N-term HIS tag, transcript variant 2)

Cytokeratin 13 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Cytokeratin 13 (full length, N-term HIS tag, transcript variant 1)

Cytokeratin 13 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Positive controls for Cytokeratin 13 (1 products)

Catalog No. Species Pres. Purity   Source  

Cytokeratin 13 Lysate

Western Blot: Cytokeratin 13 Lysate [NBL1-12380] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for KRT13
  Novus Biologicals Inc.
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