DM056 Cytokeratin 13 (+ KRT10) antibody

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1 ml / €530.00
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Mouse anti Feline, Human, Rat Cytokeratin 13 DE-K13

Product Description for Cytokeratin 13

Mouse anti Feline, Human, Rat Cytokeratin 13 DE-K13.
Properties: (+ KRT10)
Presentation: Supernatant
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.

Properties for Cytokeratin 13

Product Category Primary Antibodies
Target Category
Quantity 1 ml
Synonyms CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13
Presentation Supernatant
Reactivity Fe, Hu, Rt
Applications C, P, WB
Clonality Monoclonal
Clone DE-K13
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P13646
Immunogen:
Detergent insoluble extract of human epidermis
GeneID:
3860
Property + KRT10
Application Western Blot.
Immunohistochemistry on aceton-fixed frozen and formalin-fixed paraffin embedded tissus: use a dilution of 1:25-1:50 in an ABC method (of 30 minutes at room temperature).
Enzymatic predigestion of paraffin embedded tissues is not recommended prior to the immunostaining, as it may reduce the staining.
Recommended positive control: Skin or tonsil
Background Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
General Readings Ivanyi et al. J Pathol 159: 7, 1989.
Ivanyi et al. Differentiation 42: 124, 1989.
Ivanyi et al. Cancer Res 50: 5143, 1990.
Van Muijen et al. Exp Cell Res 171: 331, 1987.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid tissue culture supernatant containing sodium azide as preservative
Supernatant
Specificity
Specificity:
This antibody recognizes keratin polypeptides of 53 (keratin 13) and 56.5 kD (keratin 10).
It stains suprabasal cells in the epidermis, thymic Hassal's bodies, urothelium and non-cornifying stratified epithelia of vagina, ectocervix, tongue and esophagus.
The antibody does not stain intraepithelial neoplasm and invasive squamous cell carcinoma.
Cellular Localization: Cytoplasmic
Species:
Cat, Human, Rat.
Gene ID 3860
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Accessory Products

Proteins and/or Positive Controls

Proteins for Cytokeratin 13 (2 products)

Catalog No. Species Pres. Purity   Source  

Cytokeratin 13 (full length, N-term HIS tag, transcript variant 2)

Cytokeratin 13 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Cytokeratin 13 (full length, N-term HIS tag, transcript variant 1)

Cytokeratin 13 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Positive controls for Cytokeratin 13 (1 products)

Catalog No. Species Pres. Purity   Source  

Cytokeratin 13 Lysate

Western Blot: Cytokeratin 13 Lysate [NBL1-12380] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for KRT13
  Novus Biologicals Inc.
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