NBP1-22569 Cytokeratin 17 (E3) antibody

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Mouse anti Human, Rat Cytokeratin 17 (E3) E3

Product Description for Cytokeratin 17 (E3)

Mouse anti Human, Rat Cytokeratin 17 (E3) E3.
Presentation: Supernatant
Product is tested for Paraffin Sections.

Properties for Cytokeratin 17 (E3)

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms anti-CK 17 antibody, anti-K17 antibody, anti-KRT17 antibody, anti-Keratin 17 antibody, anti-PC antibody, anti-PC2 antibody
Presentation Supernatant
Reactivity Hu, Rt
Applications P
Clonality Monoclonal
Clone E3
Host Mouse
Isotype IgG2b
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Cytoskeletal fraction of rat colon epithelium.
Application immunohistochemistry, ABC, immunohistochemistry 1:25-1:50
Background Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Storage Store at 4C. Do not freeze.
Tissue culture supernatant
Buffer System:
Sodium Azide
Tissue culture supernatant
This is specific to 46 kD cytokeratin protein designated cytokeratin 17. It reacts with basal cells in complex epithelia and reacts strongly with squamous cell carcinomas.
Human, Rat

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