NBP1-22534 Cytokeratin 5+6+8+17+19 antibody

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0.5 ml / €400.00
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Mouse anti Human Cytokeratin 5+6+8+17+19 MNF116

Product Description for Cytokeratin 5+6+8+17+19

Mouse anti Human Cytokeratin 5+6+8+17+19 MNF116.
Presentation: Supernatant
Product is tested for Paraffin Sections.

Properties for Cytokeratin 5+6+8+17+19

Product Category Primary Antibodies
Quantity 0.5 ml
Presentation Supernatant
Reactivity Hu
Applications P
Clonality Monoclonal
Clone MNF116
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
BALB/C mice were immunized with crude extract of splenic cells from a nude mouse engrafted with MCF-7 cells.
Application immunohistochemistry, ABC, immunohistochemistry 1:25-1:50
Background Cytokeratins, a group of at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 4, 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Cytokeratin peptide 4 (59 kDa) is the secondary type II keratin expressed in non cornified stratified squamous epithelia. Cytokeratin peptide 5 (58 kDa) is the primary type II keratin in stratified epithelia, while cytokeratin type 8 (52 kDa) is a major type II keratin in simple epithelia. Cytokeratin 6 (56 kDa) is a "hyperproliferation" cytokeratin expressed in tissues with natural or pathological high turnover. Cytokeratins 10, 13 and 18 are members of the type I acidic subfamily. Cytokeratin peptide 10 (56 kDa) is the secondary type I keratin expressed in cornified epithelia. Cytokeratin 13 (54 kDa) is the secondary type I keratin expressed in non-cornified stratified squamous epithelial. Cytokeratin 18 (45 kDa) is the primary type I keratin expressed in simple epithelial cells.
Storage Store at 4C. Do not freeze.
Format
Purification:
Tissue culture supernatant
Buffer System:
Sodium Azide
Purity:
Tissue culture supernatant
State:
Supernatant
Specificity
Specificity:
This antibody recognizes cytokeratin polypeptides ranging from 40 through 58kD, corresponding to cytokeratins 5, 6, 8,17 and 19. It shows a broad pattern of reactivity with human epithelial tissues from simple glandular epithelial to stratified squamous epithelia, like epidermis, mammary gland ducts, and tracheal epithelium.
Species:
Human
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