NB120-3198 Cytokeratin-6 (KRT6) antibody

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Mouse anti Human, Mouse Cytokeratin-6 (KRT6) LHK6B


Product Description for Cytokeratin-6 (KRT6)

Mouse anti Human, Mouse Cytokeratin-6 (KRT6) LHK6B.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for Cytokeratin-6 (KRT6)

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms Cytokeratin-6, K6, KRT-6, KRT6A, KRT6B, KRT6C, KRT6D, KRT6E, KRTL1, Keratin type II cytoskeletal 6A, Keratin type II cytoskeletal 6B, Keratin type II cytoskeletal 6C
Presentation Purified
Reactivity Hu, Ms
Applications P
Clonality Monoclonal
Clone LHK6B
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic peptide: GSSTIKYTTTS (Human).
Isotype control AM03096PU-N
Background Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
General Readings General / background references:Machesney M et al. Activated keratinocytes in the epidermis of hypertrophic scars. Am J Pathol 152:1133-41 (1998). PubMed PMID: 9588880
Wetzels RH et al. Basal cell-specific and hyperproliferation-related keratins in human breast cancer. Am J Pathol 138:751-63 (1991). PubMed PMID: 1705754
Protein A purified
Buffer System:
10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Protein A purified
Cross-reacts with Human and Mouse.Not yet tested in other species.

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