AP51186PU-N DAZ2 (C-term) antibody

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0.4 ml / €370.00
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Quick Overview

Rabbit anti Human DAZ2

Product Description for DAZ2

Rabbit anti Human DAZ2.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DAZ2

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms Deleted in azoospermia protein 2
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q13117
Immunogen:
KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of Human DAZ2.
GeneID:
57055
Property C-term
Add. information Molecular Weight: 63111 Da
Application ELISA: 1/1000. 
Western Blot: 1/100-1/500.
Background This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Concentration lot specific
General Readings
  1.  Kim, B., et al. Hum. Reprod. 24(6):1507-1515 (2009). 
  2. Lardone, M.C., et al. Fertil. Steril. 88(5):1318-1326(2007).
  3. A, Z.C., et al. Yi Chuan 28(9):1057-1060 (2006).  
  4. Zhang, F., et al. Ann. Hum. Genet. 70 (PT 3), 304-313 (2006).
  5. Yang, Y., et al. Fertil. Steril. 85(4):1061-1063 (2006).
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Protein A column, followed by peptide affinity purification
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human DAZ2 (C-term).
Gene ID 57055

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