discontinued

ARP40250_P050 DAZ2 antibody

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Rabbit anti Bovine, Chicken, Human, Mouse, Rat, African clawed frog DAZ2

ARP40250_P050

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  • ARP40250_P050

Product Description for DAZ2

Rabbit anti Bovine, Chicken, Human, Mouse, Rat, African clawed frog DAZ2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for DAZ2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Deleted in azoospermia protein 2
Presentation Aff - Purified
Reactivity African clawed frog, Bov, Chk, Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
Q13117
Immunogen:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human DAZ2 with an internal ID of S02809
GeneID:
57055
Add. information Rabbit Ig G is purified by peptide affinity chromatography method. 59kDa, 65kDa, 65kDa, 41kDa, 65kDa, 65kDa, 63kDa, 50kDa, 44kDa
Application Suggested dilution at 0.5 ELISA titre using peptide based assay: 1:62500
Background DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
General Readings Kuo,P.L., (2004) Fertil. Steril. 81 (4), 1034-1040
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
Format
Purification:
Rabbit Ig G is purified by peptide affinity chromatography method.
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
State:
Aff - Purified
Specificity
Species:
Human
Gene ID 57055

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