AP51228PU-N DEAF1 (C-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human DEAF1

Product Description for DEAF1

Rabbit anti Human DEAF1.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DEAF1

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms Deformed epidermal autoregulatory factor 1 homolog, NUDR, Nuclear DEAF-1-related transcriptional regulator, SPN, Suppressin, ZMYND5, Zinc finger MYND domain-containing protein 5
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O75398
Immunogen:
KLH conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human DEAF1
GeneID:
10522
Property C-term
Add. information Molecular Weight: 59327 Da
Application ELISA: 1/1000.
Western Blot: 1/100-1/500.
Background
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm.
Concentration lot specific
General Readings Pilot-Storck, F., et al. Mol. Cell Proteomics 9(7):1578-1593 (2010).
Gu, B., et al. Biochem. Biophys. Res. Commun. 394(2):418-423 (2010).
Yip, L., et al. Nat. Immunol. 10(9):1026-1033 (2009).
Egli, R.J., et al. Arthritis Rheum. 60(7):2055-2064 (2009).
Barker, H.E., et al. BMC Dev. Biol. 8, 94 (2008).
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human DEAF1 (C-term).
Gene ID 10522

Accessory Products

Proteins and/or Positive Controls

Proteins for DEAF1 (7 products)

Catalog No. Species Pres. Purity   Source  

DEAF1

DEAF1 Human Purified
  Abnova Taiwan Corp.

DEAF1

DEAF1 Human Purified
  Abnova Taiwan Corp.

DEAF1

DEAF1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DEAF1

DEAF1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DEAF1

DEAF1 Human Purified
  Abnova Taiwan Corp.

DEAF1

DEAF1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DEAF1

DEAF1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for DEAF1 (1 products)

Catalog No. Species Pres. Purity   Source  

DEAF1 293T Cell Transient Overexpression Lysate(Denatured)

DEAF1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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