NB100-55821 Decoy receptor 1 antibody

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0.1 mg / €400.00

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Rabbit anti Human, Mouse, Rat Decoy receptor 1


Product Description for Decoy receptor 1

Rabbit anti Human, Mouse, Rat Decoy receptor 1.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Decoy receptor 1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Decoy TRAIL receptor without death domain, TNF-related apoptosis-inducing ligand receptor 3, Tumor necrosis factor receptor superfamily member 10C
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Human DcR1 (ED2) peptide.
Background Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.
Storage Store at 4C. Do not freeze.
Peptide Affinity Purified
Buffer System:
PBS containing 0.02% sodium azide.
Peptide Affinity Purified
Aff - Purified
Human, Mouse, Rat Not yet tested in other species.

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