NB100-62504 Dermorphin antibody

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Search for all "Dermorphin"

1 ml / €410.00

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Sheep anti All Species Dermorphin


Product Description for Dermorphin

Sheep anti All Species Dermorphin.
Product is tested for Enzyme Immunoassay.

Properties for Dermorphin

Product Category Primary Antibodies
Quantity 1 ml
Synonyms Deltorphin, Dermenkephalin
Reactivity All Species
Applications E
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic KLH conj
Application ELISA, This antibody is useful for ELISA, ELISA
Background The skin of South American frogs belonging to the genus Phyllomedusinae has been found to secrete several gene-encoded opioid peptides that contain a D-amino acid in position 2 of their sequence. Dermorphin, Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2, dermenkephalin/deltorphin A, Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2 and the deltorphins, Tyr-D-Ala-Phe-Xaa-Val-Val-Gly-NH2 (where Xaa is either Asp or Glu) are highly potent at, and exquisitely selective, for the mu- and delta-opioid receptors. Dermorphin peptides are potent analgesics in rodents and primates, including man. Some dermorphins can enter the blood-brain barrier and produce central antinociception after peripheral administration. The dermorphin family also includes mu 1-opioid receptor selective agonists that produce intense opioid analgesia, but stimulate pulmonary ventilation. Experiments in rats and mice chronically exposed to dermorphins have shown that not only do they have higher antinociceptive efficacy and potency than morphine, but they are also less likely than morphine to produce tolerance, dependence and opiate side effects.
Concentration 15.9 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer System:
0.09% Sodium Azide
All Species

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