TA336333 DIABLO / SMAC antibody

Rabbit Polyclonal SMAC/Diablo Antibody

See related secondary antibodies

Search for all "DIABLO / SMAC"

0.1 mg / €334.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human DIABLO / SMAC

TA336333

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  • TA336333

Product Description for DIABLO / SMAC

Rabbit anti Human DIABLO / SMAC.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for DIABLO / SMAC

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Diablo homolog mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase
Presentation Purified
Reactivity Hu
Applications ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9NR28
Immunogen:
This rabbit polyclonal antibody was developed against two synthetic peptides corresponding to amino acids 199 to 212 and amino acids 226 to 239 of human Smac (Genbank accession no. AAF87716).
GeneID:
56616
Application WB: 0.5-2 ug/ml
IF: 1:10-1:500
IHC-P: 1:10-1:500
Background Recently, three different laboratories have identified a molecule, Smac/DIABLO, which binds with inhibitor of apoptosis proteins (IAPs) and neutralizes IP inhibition of effector caspases. Multiple IAP molecules, including c-IAP1, c-IAP2, XIAP, and survivin are able to bind Smac. Smac/DIABLO is a mitochondrial protein, which is released into cytosol during apoptosis. The function of Smac is similar to that of Drosophila apoptosis activating proteins Reaper, Hid and Grim, which have been proposed to function by neutralizing the activity of IAPs. Smac promotes caspase-3 and caspase-9 activation by removing inhibitors rather than directly acting on Apaf-1, procaspases, and cytochrome c. The full-length cD of Smac encodes an open reading frame of 239 amino acids, predicting a protein with a molecular weight of 27 kDa. However, the mature protein purified from HeLa cells is only about 25 kDa.
Format
Purification:
Protein G purified
Buffer System:
PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for DIABLO / SMAC (12 products)

Catalog No. Species Pres. Purity   Source  

DIABLO / SMAC (transcript variant 2)

DIABLO / SMAC Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

DIABLO / SMAC (56-239)

DIABLO / SMAC Human Purified > 95 % > 95 % by SDS PAGE E. coli
0.5 mg / €990.00
  Acris Antibodies GmbH

DIABLO / SMAC (56-239)

DIABLO / SMAC Human Purified > 95 % > 95 % by SDS PAGE E. coli
0.1 mg / €340.00
  Acris Antibodies GmbH

DIABLO / SMAC

DIABLO / SMAC Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DIABLO / SMAC

DIABLO / SMAC Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DIABLO / SMAC

DIABLO / SMAC Human
  Abnova Taiwan Corp.

DIABLO / SMAC

DIABLO / SMAC Human
  Abnova Taiwan Corp.

DIABLO / SMAC

DIABLO / SMAC Human
  Abnova Taiwan Corp.

DIABLO / SMAC

SDS-Page: Smac Protein [NBC1-18509] - SMAC/Diablo, 22 kDa (199 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE Protein
  Novus Biologicals Inc.

DIABLO / SMAC (1-239)

Human DIABLO (Diablo homolog, mitochondrial) recombinant protein 6xHis-GST tagged Human Purified > 90 % 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry E. coli
  Protein Alternatives

DIABLO / SMAC (1-239)

Human DIABLO (Diablo homolog, mitochondrial) recombinant protein 6xHis-GST tagged Human Purified > 90 % 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry E. coli
  Protein Alternatives

DIABLO / SMAC (1-239)

Human DIABLO (Diablo homolog, mitochondrial) recombinant protein 6xHis-GST tagged Human Purified > 90 % 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry E. coli
  Protein Alternatives

Positive controls for DIABLO / SMAC (3 products)

Catalog No. Species Pres. Purity   Source  

DIABLO 293T Cell Transient Overexpression Lysate(Denatured)

DIABLO 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

DIABLO overexpression lysate

DIABLO overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

DIABLO overexpression lysate

DIABLO overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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