discontinued

AM50562PU-N DLG4 / PSD95 antibody

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Mouse anti Human, Mouse, Rat DLG4 / PSD95 K28/86

AM50562PU-N

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  • AM50562PU-N

Product Description for DLG4 / PSD95

Mouse anti Human, Mouse, Rat DLG4 / PSD95 K28/86.
Presentation: Purified
Product is tested for Frozen Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for DLG4 / PSD95

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
Presentation Purified
Reactivity Hu, Ms, Rt
Applications C, IP, WB
Clonality Monoclonal
Clone K28/86
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P78352
Immunogen:
Recombinant protein corresponding to a fusion domain of human PSD95/SAP90 proteins.
GeneID:
1742
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application Immunoprecipitation: A previous lot of this antibody was successfully used by an independent laboratory in IP. (Rasband, M., et al. (2002). The Journal of Cell Biology. 159(4):663–672.)
Immunohistochemistry: 1:500 dilution from a previous lot detected the MAGUK family of proteins in rat cerebellum and rat hypothalamus tissues.
Western Blot: 0.5 µg/mL of this antibody detected members of the MAGUK protein family on 10 µg of rat brain tissue lysate.
Background The MAGUKs are membrane-associated guanylate kinase related (MAGUK) proteins that are defined by their inclusion of PDZ, SH3 and GUK domains. The GUK domain that they have is structurally very similar to that of the guanylate kinases, which converts ATP into ADP. However, it is known to be catalytically inactive as the P-Loop which normally binds ATP is absent. It is thought that the MAGUKs have adopted the GUK domain for their own purposes, primarily based on its ability to form protein-protein interactions with cytoskeleton proteins, microtubule/actin based machinery and molecules involved in signal transduction. In addition many of the MAGUK proteins also contain regions homologous of CaMKII, WW and L27 domains. Some of the members of the MAGUK family of proteins include DLG4 (Disks large homolog 4), DLG2, PSD95, MPP1 and other cytoskeleton-interacting proteins.
Concentration lot-specific
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography
Buffer System:
0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
State:
Liquid purified Ig fraction
Purified
Specificity
Specificity:
This antibody exhibits cross reactivity against recombinant Chapsyn-110, SAP97, and SAP102. (UC Davis/NIH NeuroMab Facility, http://neuromab.ucdavis.edu)
Demonstrated to react with rat. Predicted to react with human based on immunogen design. Predicted to react with mouse based on 100% sequence homology.

Accessory Products

Proteins and/or Positive Controls

Proteins for DLG4 / PSD95 (5 products)

Catalog No. Species Pres. Purity   Source  

DLG4 / PSD95 (transcript variant 1)

DLG4 / PSD95 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DLG4 / PSD95

DLG4 / PSD95 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DLG4 / PSD95

DLG4 / PSD95 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DLG4 / PSD95

DLG4 / PSD95 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DLG4 / PSD95

DLG4 / PSD95 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for DLG4 / PSD95 (1 products)

Catalog No. Species Pres. Purity   Source  

PSD95 Lysate

Western Blot: PSD95 Lysate [NBL1-09911] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for DLG4.
  Novus Biologicals Inc.
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