discontinued

AP26008PU-N DLG4 / PSD95 antibody

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Goat anti Bovine, Canine, Human, Mouse, Rat DLG4 / PSD95

Product Description for DLG4 / PSD95

Goat anti Bovine, Canine, Human, Mouse, Rat DLG4 / PSD95.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DLG4 / PSD95

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
Presentation Aff - Purified
Reactivity Bov, Can, Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P78352
Immunogen:
Peptide from the internal region (near C-Terminus) of the protein sequence according to NP_001356.1; NP_001122299.1.
AA Sequence:
C-EEQARKAFDRATK
GeneID:
1742
Application Peptide ELISA: 1/64000 (Detection Limit).
Western blot: 0.3-1 µg/ml. Approx 85kDa band observed in Mouse and Rat Brain lysates (calculated MW of 85.4kDa according to NP_001356.1).
Background PSD95 is a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Concentration 0.5 mg/ml
General Readings
  1. Marks DR, Fadool DA. Post-synaptic density perturbs insulin-induced Kv1.3 channel modulation via a clustering mechanism involving the SH3 domain. J Neurochem. 2007 Nov;103(4):1608-27. Epub 2007 Sep 13. PubMed PMID: 17854350. (Free PMC Article available, 10 images available)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Buffer System:
Tris saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Human, Dog, Cow.
Species reactivity (tested):
Mouse, Rat.
Specificity
Specificity:
This antibody detects DLG4 / PSD95 (Internal).
It is expected to recognize both reported isoforms (NP_001356.1, NP_001122299.1).
Gene ID 1742

Accessory Products

Proteins and/or Positive Controls

Proteins for DLG4 / PSD95 (5 products)

Catalog No. Species Pres. Purity   Source  

DLG4 / PSD95 (transcript variant 1)

DLG4 / PSD95 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DLG4 / PSD95

DLG4 / PSD95 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DLG4 / PSD95

DLG4 / PSD95 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DLG4 / PSD95

DLG4 / PSD95 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DLG4 / PSD95

DLG4 / PSD95 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for DLG4 / PSD95 (1 products)

Catalog No. Species Pres. Purity   Source  

PSD95 Lysate

Western Blot: PSD95 Lysate [NBL1-09911] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for DLG4.
  Novus Biologicals Inc.
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