TA309223 DLG4 / PSD95 (N-term) antibody

Rabbit Anti-PSD-95 Antibody

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Search for all "DLG4 / PSD95"

0.1 ml / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Bovine, Human, Mouse, Rat, Zebrafish DLG4 / PSD95

Product Description for DLG4 / PSD95

Rabbit anti Bovine, Human, Mouse, Rat, Zebrafish DLG4 / PSD95.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DLG4 / PSD95

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
Presentation Aff - Purified
Reactivity Bov, Hu, Ms, non-Human Primates, Rt, Ze
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P31016
Immunogen:
Peptide corresponding to amino acid residues from the N-terminal region of Rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH).
GeneID:
29495
Property N-term
Application Western blot: 1/1,000.
Background PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).
General Readings
  1. Chung HJ, Huang YH, Lau LF, Huganir RL. Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand. J Neurosci. 2004 Nov 10;24(45):10248-59. PubMed PMID: 15537897.
  2. Kim EJ, Sheng M (2004) PDZ domain proteins of synapses. Nat Rev Neurosci 5:771-781.
Storage Store the antibody undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography.
Buffer System:
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% Glycerol.
State:
Liquid purified Ig fraction.
Aff - Purified
Species Reactivity
Species reactivity (expected):
Human, Bovine, Zebrafish and non-Human Primates.
Species reactivity (tested):
Rat and Mouse.
Specificity
Specificity:
This antibody recognizes the ~95k PSD95 protein.

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