AP51302PU-N DNMT3A (Center) antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human DNMT3A

Product Description for DNMT3A

Rabbit anti Human DNMT3A.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DNMT3A

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms DNA (cytosine-5)-methyltransferase 3A, DNA MTase HsaIIIA, DNA methyltransferase HsaIIIA, M.HsaIIIA
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y6K1
Immunogen:
KLH conjugated synthetic peptide selected from the Central region of Human DNMT3A
GeneID:
1788
Property Center
Add. information Molecular Weight: 101858 Da
Application

ELISA: 1/1000.
Western Blot: 1/100-1/500.

Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Concentration lot specific
General Readings
  1. Holz-Schietinger, C., et al. J. Biol. Chem. 285(38):29091-29100 (2010). 
  2. Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1822-1830 (2010).
  3. Park, C.W., et al. J Cardiovasc Transl Res 3(3):290-295 (2010). 
  4. Haggarty, P., et al. PLoS ONE 5 (6), E11329 (2010). 
  5. Zhao, Z., et al. J. Biomed. Biotechnol. 2010, 737535 (2010)  
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human DNMT3A (Center).
Gene ID 1788

Accessory Products

Proteins and/or Positive Controls

Proteins for DNMT3A (6 products)

Catalog No. Species Pres. Purity   Source  

DNMT3A (transcript variant 3)

DNMT3A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DNMT3A

DNMT3A Human Purified
  Abnova Taiwan Corp.

DNMT3A

DNMT3A Human Purified
  Abnova Taiwan Corp.

DNMT3A

DNMT3A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DNMT3A

DNMT3A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

DNMT3A

DNMT3A Human
  Abnova Taiwan Corp.

Positive controls for DNMT3A (5 products)

Catalog No. Species Pres. Purity   Source  

DNMT3A 293T Cell Transient Overexpression Lysate(Denatured)

DNMT3A 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

Dnmt3a Lysate

Western Blot: Dnmt3a Lysate [NBL1-09970] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for DNMT3A
  Novus Biologicals Inc.

DNMT3A overexpression lysate

DNMT3A overexpression lysate
  OriGene Technologies, Inc.

DNMT3A overexpression lysate

DNMT3A overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

DNMT3A overexpression lysate

DNMT3A overexpression lysate
  OriGene Technologies, Inc.
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