AP55813PU-S DPYSL2 / CRMP2 pThr509 antibody

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50 µg / €270.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat DPYSL2 / CRMP2

AP55813PU-S

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  • AP55813PU-S

Product Description for DPYSL2 / CRMP2

Rabbit anti Human, Mouse, Rat DPYSL2 / CRMP2.
Properties: pThr509
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for DPYSL2 / CRMP2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Collapsin response mediator protein 2, DRP-2, Dihydropyrimidinase-related protein 2, N2A3
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight 50 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q16555
Immunogen:
Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from Human CRMP-2 (KLH-conjugated)
GeneID:
1808
Property pThr509
Application Western blot: 1:500~1:1000.
Immunohistochemistry on paraffin sections: 1:50~1:100.
Background CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Concentration 1.0 mg/ml
General Readings
  1. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 1994 Oct 7;266(5182):66-71. PubMed PMID: 7545954.
  2. Smith TM, Lee MK, Szabo CI, Jerome N, McEuen M, Taylor M, et al. Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res. 1996 Nov;6(11):1029-49. PubMed PMID: 8938427.
  3. Wilson CA, Payton MN, Elliott GS, Buaas FW, Cajulis EE, Grosshans D, et al. Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b. Oncogene. 1997 Jan 9;14(1):1-16. PubMed PMID: 9010228.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography using epitope-specific peptide
Buffer System:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat
Specificity
Specificity:
The antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.

Accessory Products

Proteins and/or Positive Controls

Proteins for DPYSL2 / CRMP2 (4 products)

Catalog No. Species Pres. Purity   Source  

DPYSL2 / CRMP2

DPYSL2 / CRMP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DPYSL2 / CRMP2

DPYSL2 / CRMP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DPYSL2 / CRMP2

DPYSL2 / CRMP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

DPYSL2 / CRMP2

DPYSL2 / CRMP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.
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