discontinued

SP6264P DRAK1 (5-19) antibody

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Search for all "DRAK1 (5-19)"

50 µg / €210.00

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Rabbit anti Human, Mouse, Rat DRAK1 (5-19)

SP6264P

Product Description for DRAK1 (5-19)

Rabbit anti Human, Mouse, Rat DRAK1 (5-19).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DRAK1 (5-19)

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer AnaSpec

Datasheet Extract

Immunogen
Immunogen:
A synthetic peptide corresponding to amino acids 5 to 19 of human DRAK1 (1).






Format: This antibody is supplied as liquid Protein G purified immunglobulin fraction in Phosphate buffered saline with 0.02% sodium azide as preservative.
Application Suitable for Western blot (1/500 - 1/1000, A431 or MOLT4 whole cell lysate can be used as positive control and an approximately 50 kDa band can be detected). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
General Readings
  1. Sanjo H, Kawai T, Akira S. DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis. J Biol Chem. 1998 Oct 30;273(44):29066-71. PubMed PMID: 9786912.
Storage Store the antibody undiluted at 4-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf life: one year from despatch.
Format
State:
Aff - Purified
Specificity
Specificity:
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissue (1).
This antibody reacts with human DRAK1 (NT).

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