bs-8863R DUOXA2 antibody

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Rabbit anti Human, Mouse, Rat DUOXA2


Product Description for DUOXA2

Rabbit anti Human, Mouse, Rat DUOXA2.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for DUOXA2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms DOXA2_HUMAN, Dual oxidase activator 2, Dual oxidase activator 2.., Dual oxidase maturation factor 2, Dual oxidase maturation factor-2, SIMNIPHOM, TDH5
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide derived from human DUOXA2.
Application WB(1:100-1000)
Background DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family. Expressed specifically in thyroid and salivary glands, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH). Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth. The gene encoding DUOXA2 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Storage Store at -20°C for 12 months.
Purified by Protein A.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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