AP54899SU-N Dynactin subunit 1 antibody

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0.2 ml / €400.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Drosophila Dynactin subunit 1

AP54899SU-N

Product Description for Dynactin subunit 1

Rabbit anti Drosophila Dynactin subunit 1.
Presentation: Serum
Product is tested for Frozen Sections, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Dynactin subunit 1

Product Category Primary Antibodies
Quantity 0.2 ml
Presentation Serum
Reactivity Dros
Applications C, E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P13496
Immunogen:
Synthetic peptide derived from N-terminal domain of the Drosophila melanogaster DCTN1 protein.
GeneID:
39536
Application

ELISA.
Western Blot: 1/500-1/5000.
Immunohistochemistry: 1/100-1/500.

Background The DCTN1 gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein. Alternative splicing of this gene results in at least 2 functionally distinct isoforms: a ubiquitously expressed one and a brain-specific one. Based on its cytogenetic location, this gene is considered as a candidate gene for limb-girdle muscular dystrophy.
Storage

Prior to reconstitution store the antibody at -20°C.
Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
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Format
Preservatives:
None
State:
Lyophilized serum
Serum
Reconstitution:
Restore in distilled water.
Specificity
Specificity:
This antibody reacts with 141 kDa DAP-150 from Drosophila melanogaster.
Gene ID 39536

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