AP26039PU-S EIF2B / EIF2S2 pSer2 antibody

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50 µl / €240.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse EIF2B / EIF2S2

Product Description for EIF2B / EIF2S2

Rabbit anti Human, Mouse EIF2B / EIF2S2.
Properties: pSer2
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for EIF2B / EIF2S2

Product Category Primary Antibodies
Target Category
Quantity 50 µl
Synonyms Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, eIF2-beta
Presentation Aff - Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P20042
Immunogen:
Peptide sequence around phosphorylation site of serine 2 derived from eIF2β.
AA Sequence:
M-S(p)-G-D-E
GeneID:
8894
Property pSer2
Add. information Molecular weight: 38 kDa
Application Western blot: 1:500 - 1:1000.
Background eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Concentration 1.0 mg/ml
General Readings
  1. Pathak VK, Nielsen PJ, Trachsel H, Hershey JW. Structure of the beta subunit of translational initiation factor eIF-2. Cell. 1988 Aug 26;54(5):633-9. PubMed PMID: 3044606.
Storage Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity-chromatography using epitope-specific peptide
Buffer System:
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse
Specificity
Specificity:
This antibody detects endogenous levels of eIF2β only when phosphorylated at serine 2.
Gene ID 8894

Accessory Products

Proteins and/or Positive Controls

Proteins for EIF2B / EIF2S2 (5 products)

Catalog No. Species Pres. Purity   Source  

EIF2B / EIF2S2

EIF2B / EIF2S2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

EIF2B / EIF2S2

EIF2B / EIF2S2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
  Abnova Taiwan Corp.

EIF2B / EIF2S2

EIF2B / EIF2S2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
  Abnova Taiwan Corp.

EIF2B / EIF2S2

EIF2B / EIF2S2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

EIF2B / EIF2S2

EIF2B / EIF2S2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for EIF2B / EIF2S2 (1 products)

Catalog No. Species Pres. Purity   Source  

EIF2beta Lysate

Western Blot: EIF2 beta Lysate [NBL1-10187] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for EIF2C3.
  Novus Biologicals Inc.
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