GTX10290 Endomorphin 1 & 2 antibody

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Search for all "Endomorphin 1 & 2"

50 µg / €340.00

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Rabbit anti Human, Monkey, Mouse, Porcine, Rat Endomorphin 1 & 2

Product Description for Endomorphin 1 & 2

Rabbit anti Human, Monkey, Mouse, Porcine, Rat Endomorphin 1 & 2.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay.

Properties for Endomorphin 1 & 2

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu, Mky, Ms, Por, Rt
Applications C, E
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide conjugated to BSA.
Application ELISA, IHC-Fr
Background Recently, endogenous agonists for the mu-opiate receptor, were first isolated from bovine brain [Nature,386, 499 (1997)]. These are endomorphin-1; Tyr-Pro-Trp-Phe-NH2, and endomorphin-2; Tyr-Pro-Phe-Phe-NH2. The isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex has also reported [Peptides,18, 1635 (1997)].The immunoreactivity for endomorphin was also detected in rat brain near the mu-opiate receptor containing neurons, but the molecular form of the rat peptide has not yet been elucidated [Peptides,18, 1641 (1997)]. These observations may be considered to indicate that endomorphin-1 and 2 are common mu-opiate agonists in mammals. In addition to the originally discovered mu-opiate agonistic function, these peptides have been reported to show hypotensive activity and Ca2+ channel current inhibitory activity [Biochem. Biophys. Res. Commun.,235, 567 (1997)]. Endomorphins would be useful for the study of pain perception together with some other biological functions in the body.
Storage Keep as concentrated solution. Store at 4
Immunogen affinity purified
Immunogen affinity purified
Aff - Purified
Cross-reacts with Human, Mouse, Rat, Monkey and Pig. Not yet tested in other species.

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