AP01580PU-N Ephrin-B1/2 pTyr330 antibody

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Rabbit anti Human, Mouse, Rat Ephrin-B1/2

Product Description for Ephrin-B1/2

Rabbit anti Human, Mouse, Rat Ephrin-B1/2.
Properties: pTyr330
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Ephrin-B1/2

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms EFL-3, EFL3, EFNB1, EFNB2, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPH-related receptor tyrosine kinase ligand 5, EPLG2, EPLG5, Ephrin-B1, Ephrin-B2, HTK ligand, HTK-L, LERK-2, LERK-5, LERK2
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 42 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Property pTyr330
Application Western Blot: 1/500-1/1000.
Background Ephrins, which act as ligands for Eph receptors, are cell-surface proteins which fall into two categories, ephrin-A and ephrin-B based on their structure and function. Ephrin-B proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development.
Concentration 1.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
Phosphate buffered saline (PBS), pH~7.2 containing 0.05% Sodium Azide as preservative.
Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Aff - Purified
This antibody detects endogenous levels of Ephrin-B pTyr330 protein.
Human, Mouse and Rat.

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