AM33244SU-N Epstein Barr Virus / EBV (LMP1) antibody

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0.1 ml / €380.00

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Mouse anti Epstein Barr Virus / EBV CS1/CS2/CS3/CS4


Product Description for Epstein Barr Virus / EBV

Mouse anti Epstein Barr Virus / EBV CS1/CS2/CS3/CS4.
Properties: (LMP1)
Presentation: Supernatant
Product is tested for Paraffin Sections, Frozen Sections.

Properties for Epstein Barr Virus / EBV

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms HHV-4, HHV4
Presentation Supernatant
Applications C, P
Clonality Monoclonal
Clone CS1/CS2/CS3/CS4
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Recombinant fusion protein of bacterial beta-galactosidase and EBV LMP-1. 
Spleen cells from immunised mice were fused with cells of the mouse X63-Ag8.653 myeloma cell line.
Property LMP1
Immunohistochemistry on Paraffin Sections:
Requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.
Background EBV is a human herpesvirus that establishes a life-long persistence in the host. The virus infects the vast majority of the world's adult population and is well known for its association with a broad spectrum of benign and malignant diseases, including infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma, and is causally associated with lymphoid and epithelial malignancies, including post-transplant lymphoproliferative disorders, Hodgkin's disease, anaplastic nasopharyngeal carcinoma and gastric carcinomas. Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is a transforming protein that affects multiple cell signalling pathways and contributes to EBV-associated oncogenesis. LMP1 can be expressed in some states of EBV latency, and significant induction of full-length LMP1 is also observed frequently during virus reactivation into the lytic cycle. LMP1 is critical for EBV-infected cell activation, adhesion and survival, and is usually expressed in the malignant cells.
General Readings
  1. Murray PG, Young LS, Rowe M, Crocker J. Immunohistochemical demonstration of the Epstein-Barr virus-encoded latent membrane protein in paraffin sections of Hodgkin's disease. J Pathol. 1992 Jan;166(1):1-5. PubMed PMID: 1311374.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
15mM Sodium Azide
Liquid Tissue Culture Supernatant
This Mouse anti Epstein-Barr Virus LMP antibody, Clone CS1/CS2/CS3/CS4 is a cocktail of 4 antibodies recognising different epitopes of Epstein Barr Virus Latent Membrane Protein (LMP).
Mouse anti Epstein-Barr Virus LMP antibody, Clone CS1/CS2/CS3/CS4 stains EBV positive lymphoblastoid cell lines and EBV infected B cells in infectious mononucleosis.

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