discontinued

AP22959PU-N ERCC2 antibody

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Goat anti Bat, Bovine, Canine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit ERCC2

Product Description for ERCC2

Goat anti Bat, Bovine, Canine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit ERCC2.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for ERCC2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms CXPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, XPD, XPDC, Xeroderma pigmentosum group D-complementing protein
Presentation Aff - Purified
Reactivity Bov, Bt, Can, Elephant, Hst, Hu, Mky, Ms, Por, Rb
Applications P
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P18074
Immunogen:
Synthetic peptide from human ERCC2 / XPD
GeneID:
2068
Remarks:
Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Hamster, Elephant, Panda, Dog, Bat, Bovine, Rabbit, Pig (100%); Rat, Opossum, Salmon, Stickleback, Seq squirt, Sea anemone, Capsaspora (92%); Zebrafish (83%)
Application Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Background The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Concentration 0.5 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity Chromatography
Buffer System:
Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Gorilla, Monkey, Marmoset, Mouse, Hamster, Elephant, Panda, Dog, Bat, Bovine, Rabbit, Pig, Rat, Opossum, Salmon, Stickleback, Seq squirt, Sea anemone, Capsaspora, Zebrafish
Specificity
Specificity:
This antibody reacts to DNA-repair Protein Complementing Xp-d Cells (ERCC2).
Gene ID 2068

Accessory Products

Proteins and/or Positive Controls

Proteins for ERCC2 (4 products)

Catalog No. Species Pres. Purity   Source  

ERCC2

ERCC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ERCC2

ERCC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ERCC2

ERCC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ERCC2

ERCC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for ERCC2 (4 products)

Catalog No. Species Pres. Purity   Source  

ERCC2 293T Cell Transient Overexpression Lysate(Denatured)

ERCC2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

ERCC2 overexpression lysate

ERCC2 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

ERCC2 overexpression lysate

ERCC2 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

XPD Lysate

Western Blot: XPD Lysate [NBL1-10320] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ERCC2
  Novus Biologicals Inc.
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