AM20636PU-N ERK1 / ERK2 antibody

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0.1 mg / €340.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human, Insect, Mouse, Rat, Yeast ERK1 / ERK2 IL-13

AM20636PU-N

Product Description for ERK1 / ERK2

Mouse anti Human, Insect, Mouse, Rat, Yeast ERK1 / ERK2 IL-13.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for ERK1 / ERK2

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms ERK-1/ERK-2, MAPK1/MAPK2, P42/P44-MAPK
Presentation Purified
Reactivity Hu, Insect, Ms, Rt, Ye
Applications ICC/IF, P, WB
Clonality Monoclonal
Clone IL-13
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application Western Blot: 0.25 - 0.5 μg/ml.
Immunohistochemistry on paraffin sections: 0.4 - 1 μg/ml.
Immunocytochemistry.
Background In mammalian cells, a variety of extracellular stimuli generate intracellular signals that converge on a limited number of so-called mitogen-activated protein (MAP) kinase pathways. The central core of each MAP kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.
Concentration 0,1 mg/ml (after reconstitution with PBS)
General Readings
  1. Rodriguez-Viciana P, Tetsu O, Tidyman WE, Estep AL, Conger BA, Cruz MS, et al. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome. Science. 2006 Mar 3;311(5765):1287-90. Epub 2006 Jan 26. PubMed PMID: 16439621.
  2. Scholl FA, Dumesic PA, Barragan DI, Harada K, Bissonauth V, Charron J, et al. Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia. Dev Cell. 2007 Apr;12(4):615-29. PubMed PMID: 17419998.
Storage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
State:
Lyphilized purified Ig fraction
Purified
Reconstitution:
Restore with 1.2% sodium acetate or neutral PBS
Specificity
Specificity:
This antibody reacts to ERK1 / ERK2.
Species:
Human, Mouse, Rat, Yeast.

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