AP02742PU-N ERK1 / ERK2 antibody

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0.1 ml / €270.00
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Quick Overview

Rabbit anti Human, Mouse ERK1 / ERK2

Product Description for ERK1 / ERK2

Rabbit anti Human, Mouse ERK1 / ERK2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for ERK1 / ERK2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms ERK-1/ERK-2, Extracellular signal regulated kinase 1/2, Insulin stimulated MAP2 kinase, MAPK1/MAPK2, Microtubule associated protein 2 kinase, Mitogen activated protein kinase 1/2/3, P42/P44-MAPK
Presentation Aff - Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human p44/42 MAP Kinase around the phosphorylation site of tyrosine 204 (T-E-YP-V-A).
Application Western Blot: 1:500~1:1000.
Background Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs through phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine.
Concentration 1.0 mg/ml
General Readings
  1. TETE HANNKEN, et al. (2000) Am Soc Nephrol 11:1387-1397
  2. Omar D. PerezNature et al. (2002) Biotechnology 20: 155 - 162
  3. Jingui Yu, et al. (2005) Anesth Analg 101: 315-321
  4. Hironobu Ihn et al.(2000) Immunology 165: 2149-2155
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer System:
PBS(without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid purified IgG
Aff - Purified
Specificity
Specificity:
p44/42 MAP Kinase antibody detects endogenous levels of total p44/42 MAP Kinase protein.
Species:
Human, Mouse, Rat.
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