GTX17942 ERK1 / ERK2 antibody

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50 µl / €380.00

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Rabbit anti Bovine, Human, Mouse, Rat ERK1 / ERK2

Product Description for ERK1 / ERK2

Rabbit anti Bovine, Human, Mouse, Rat ERK1 / ERK2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for ERK1 / ERK2

Product Category Primary Antibodies
Quantity 50 µl
Synonyms ERK-1/ERK-2, Extracellular signal regulated kinase 1/2, Insulin stimulated MAP2 kinase, MAPK1/MAPK2, Microtubule associated protein 2 kinase, Mitogen activated protein kinase 1/2/3, P42/P44-MAPK
Presentation Aff - Purified
Reactivity Bov, Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide, corresponding to C terminal amino acids 317-339 of Human ERK1 + ERK2.
Application WB
Background ERK (extracellular signal regulated kinase), also known as MAPK (mitogen-activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, respectively. These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, hormones, growth factors, cytokines, and bioactive peptides. Cell stimulation induces the activation of a signaling cascade, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton. ERK1 and ERK2 are phosphorylated within the activation loop on both a Threonine and a Tyrosine residue (within a Thr-Glu-Tyr motif) by MEKs (MAPK/ERK kinases), thereby greatly elevating the activity of ERK1&2.
Storage Keep as concentrated solution. Store at 4
Immunogen affinity purified
Buffer System:
Preservative: 0.05% Sodium Azide. Constituents: 50% Glycerol, PBS, 1mg/ml BSA. pH 7.3
Immunogen affinity purified
Aff - Purified
Cross-reacts with Human, Mouse, Rat and Cow. Not yet tested in other species.

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