discontinued

GTX24819 ERK1 / ERK2 pThr185/202 antibody

See related secondary antibodies

Search for all "ERK1 / ERK2"

50 µl / €320.00

Quick Overview

Rabbit anti Human ERK1 / ERK2

GTX24819

More Views

  • GTX24819

Product Description for ERK1 / ERK2

Rabbit anti Human ERK1 / ERK2.
Properties: pThr185/202
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for ERK1 / ERK2

Product Category Primary Antibodies
Quantity 50 µl
Synonyms ERK-1/ERK-2, Extracellular signal regulated kinase 1/2, Insulin stimulated MAP2 kinase, MAPK1/MAPK2, Microtubule associated protein 2 kinase, Mitogen activated protein kinase 1/2/3, P42/P44-MAPK
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide (Human) derived from the region of ERK 1 + 2 that contains threonine 202/185 and tyrosine 204/187, based on the human sequence. This region is conserved among many species including rat, mouse, cow, frog, snail, nematode, and fruit fly.
Property pThr185/202
Application WB
Background ERK (extracellular signal-regulated kinase), also known as MAPK (mitogen-activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, respectively. These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, hormones, growth factors, cytokines, and bioactive peptides. Cell stimulation induces the activation of a signalling cascade, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton. ERK 1 and ERK 2 are fully activated by phosphorylation within a Thr-Glu-Tyr motif of the activation loop on both a threonine and a tyrosine residue by MEKs (MAPK/ERK kinases), thereby greatly elevating the activity of the ERK 1 + 2 enzymes.
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Immunogen affinity purified
Buffer System:
Preservative: 0.05% Sodium Azide; Constituents: 50% Glycerol, PBS, 1mg/ml BSA (IgG, protease free). pH 7.3
Purity:
Immunogen affinity purified
State:
Liquid
Aff - Purified
Specificity
Specificity:
Cross-reacts with Human. Expected to cross-react with a wide range of other species due to sequence homology. Not yet tested in other species.

Accessory Products

  • LinkedIn