NB100-75580 ERK2 antibody

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Chicken anti Human, Mouse, Rat ERK2


Product Description for ERK2

Chicken anti Human, Mouse, Rat ERK2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for ERK2

Product Category Primary Antibodies
Quantity 0.05 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Chicken
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

The immunogen for this antibody was a sequence from 232a.a. to 360a.a. from ERK2(a 360a.a. long protein)
Application Western Blot
Background ERK2 is activated by MEK2, which phosphorylates neighbouring threonine 183 and tyrosine 185 residues. ERK2 is a serine/threonine kinase that phosphorylates MAP2 and myelin basic protein. This kinase is an important proximal componant of the MAP kinase pathway involved in transmitting the signals from growth factors, neurotransmitters and hormones at the cell surface to the transcriptional events in the nucleus.
General Readings 1. Coltella,N., Rasola,A., Nano,E., Bardella,C., Fassetta,M., Filigheddu,N., Graziani,A., Comoglio,P.M. and Di Renzo,M.F.
p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy-induced apoptosis
2. Hemonnot,B., Molle,D., Bardy,M., Gay,B., Laune,D., Devaux,C. and Briant,L.
Phosphorylation of the HTLV-1 matrix L-domain-containing protein by virus-associated ERK-2 kinase
3. Gesty-Palmer,D., Chen,M., Reiter,E., Ahn,S., Nelson,C.D., Wang,S., Eckhardt,A.E., Cowan,C.L., Spurney,R.F., Luttrell,L.M. and, et al.
Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
4. Smith,O.P., Battersby,S., Sales,K.J., Critchley,H.O. and Jabbour,H.N.
Prostacyclin receptor up-regulates the expression of angiogenic genes in human endometrium via cross talk with epidermal growth factor Receptor and the extracellular signaling receptor kinase 1/2 pathway
5. Li,Z., Hosoi,Y., Cai,K., Tanno,Y., Matsumoto,Y., Enomoto,A., Morita,A., Nakagawa,K. and Miyagawa,K.
Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation
6. , Owaki H., Makar R., Boulton T.G., Cobb M.H., Geppert T.D.
Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs.
7. , Gonzalez F.A., Raden D.L., Rigby M.R., Davis R.J.
Heterogeneous expression of four MAP kinase isoforms in human tissues.
8. , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
9. , Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
10. , Greenway A.L., Azad A., Mills J., McPhee D.A.
Human immunodeficiency virus type 1 Nef binds directly to LCK and mitogen-activated protein kinase, inhibiting kinase activity.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
Phosphate-Buffered Saline.
Immunogen affinity purified
Aff - Purified
This antibody is reactive against Human, mouse, rat.

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