discontinued

AP30326PU-N FABP7 (Center) antibody

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0.1 mg / €360.00

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Rabbit anti Human FABP7

AP30326PU-N

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  • AP30326PU-N

Product Description for FABP7

Rabbit anti Human FABP7.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for FABP7

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms B-FABP, BLBP, Fatty acid binding protein 7, MRG
Presentation Aff - Purified
Reactivity Hu
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9H047
Immunogen:
FABP7 antibody was raised against a 17 amino acid peptide from near the center of human FABP7. (AP30326CP-N)
Property Center
Control peptide AP30326CP-N
Add. information Blocking peptide available: blocking peptide (AP30326CP-N)
Application ELISA.
Western Blot: 0.5 – 1 μg/ml.
Immunohistochemistry.
Background FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
Concentration 1 mg/ml
General Readings
  1. Shimizu F, Watanabe TK, Shinomiya H, Nakamura Y, Fujiwara T. Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochim Biophys Acta. 1997 Oct 9;1354(1):24-8. PubMed PMID: 9375786.
  2. Chmurzyńska A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J Appl Genet. 2006;47(1):39-48. PubMed PMID: 16424607.
  3. Arai Y, Funatsu N, Numayama-Tsuruta K, Nomura T, Nakamura S, Osumi N. Role of Fabp7, a downstream gene of Pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J Neurosci. 2005 Oct 19;25(42):9752-61. PubMed PMID: 16237179.
  4. Goto Y, Matsuzaki Y, Kurihara S, Shimizu A, Okada T, Yamamoto K, et al. A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res. 2006 Apr 15;66(8):4443-9. PubMed PMID: 16618771.
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide.
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody reacts to FABP7.
Species:
Human.

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