SM1758 Factor H antibody

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Mouse anti Human, Monkey Factor H OX-24


Product Description for Factor H

Mouse anti Human, Monkey Factor H OX-24.
Presentation: Supernatant
Product is tested for Enzyme Immunoassay, Immunoprecipitation, Western blot / Immunoblot.

Properties for Factor H

Product Category Primary Antibodies
Quantity 5 ml
Presentation Supernatant
Reactivity Hu, Mky
Applications E, IP, WB
Clonality Monoclonal
Clone OX-24
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Human complement factor H

Format: This antibody is supplied as liquid, Tissue Culture Supernatant with 0.09% sodium azide as preservative.
Application Immunoprecipitation. Western blotting. ELISA. 1/500 as detecting antibody. Not suitable for Flow cytometry. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
General Readings
  1. Alsenz J, Schulz TF, Lambris JD, Sim RB, Dierich MP. Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H. Biochem J. 1985 Dec 15;232(3):841-50. PubMed PMID: 2936333. (Free PMC Article available)
  2. Fontaine, M. et al. (1989). Truncated forms of human complement factor H. Biochem. J. 258: 927-930.
  3. Sim, E. et al. (1983). Monoclonal antibodies against the complement control protein
Storage Store the antibody at 4-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
This antibody recognises the human serum complement protein factor H (155kD), binding to a different epitope from MRC OX23. The antibody also recognises a 43-49kD truncated form of factor H present at low level (1-5 mg/ml) in plasma and urine. In an immunoprecipitation system, it recognises factor H in other primates, but not in cow, sheep, pig, chicken or rabbit sera. Factor H occurs on the surface of some myeloid cell lines, and antibody will bind to its epitope on U937 and some B lymphoblastoid cell lines. This antibody inhibits the binding of factor H to surface bound C3b, and recognises Factor H in Western blotting procedures.

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