GTX12432 Farnesyl antibody

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50 µl / €380.00

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Rabbit anti Farnesyl


Product Description for Farnesyl

Rabbit anti Farnesyl.
Presentation: Serum
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence.

Properties for Farnesyl

Product Category Primary Antibodies
Quantity 50 µl
Presentation Serum
Applications E, ICC/IF
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

N-acetyl-S-farnesyl-L-cysteine conjugated to KLH.
Application ELISA, IF
Background Isoprenylation/methylation is an important posttranslational lipid modification; the covalent addition of a 15 carbon farnesyl or a 20-carbon geranylgeranyl group to the C-terminus of a protein results in a substantial increase in hydrophobicity. All known G proteins are modified in this way, making the pathway of central interest for an understanding of signal transduction. From nematode to human, many eukaryotic proteins are reported to be isoprenylated. Known prenylated proteins include fungal mating factors, nuclear lamins, Ras and Ras-related GTP-binding proteins (G proteins), and the subunits of trimeric G proteins, protein kinases and at least one viral protein. Prenylation promotes membrane interactions of most of these proteins, which is not surprising given the hydrophobicity of the lipids involved. In addition, prenylation appears to play a major role in several protein-protein interactions.
Concentration whole antiserum
Storage Keep as concentrated solution. Store at 4
Whole antiserum
Buffer System:
whole serum containing 0.2% sodium azide
Whole antiserum
Not species specific.

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