GTX19364 fetal hemoglobin antibody

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1 mg / €510.00

Quick Overview

Sheep anti Human, Monkey fetal hemoglobin


Product Description for fetal hemoglobin

Sheep anti Human, Monkey fetal hemoglobin.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for fetal hemoglobin

Product Category Primary Antibodies
Quantity 1 mg
Presentation Aff - Purified
Reactivity Hu, Mky
Applications E, ICC/IF, WB
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Human Hemoglobin F
Application ELISA, ICC, WB
Background The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'
Concentration 1 mg/ml
Storage Keep as concentrated solution, aliquot and store at 4
Immunogen affinity purified
Buffer System:
Preservative: 0.1% Sodium Azide. Constituents: PBS. pH 7.2
Immunogen affinity purified
Aff - Purified
Cross-reacts with Human. Expected to cross-react with Chimpanzee (100% identity with immunogen), Gorilla (99% identity with immunogen) and Rhesus monkey (97% identity with immunogen) due to sequence homology. Not yet tested in other species.

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