bs-10092R FGFR1 / PLAG1 fusion antibody

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Rabbit anti Human, Mouse, Rat FGFR1 / PLAG1 fusion

Product Description for FGFR1 / PLAG1 fusion

Rabbit anti Human, Mouse, Rat FGFR1 / PLAG1 fusion.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for FGFR1 / PLAG1 fusion

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms FGFR1/PLAG1 fusion variant 3
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide derived from human PLAG1.
Background PLAG1 is a transcription factor whose activation results in upregulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with upregulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.
Storage Store at -20°C for 12 months.
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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