R1152HRPS Fibrinogen antibody

See related secondary antibodies

Search for all "Fibrinogen"

0.1 mg / €440.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Goat anti Human Fibrinogen


Product Description for Fibrinogen

Goat anti Human Fibrinogen.
Presentation: HRP
Product is tested for Western blot / Immunoblot, Paraffin Sections, Enzyme Immunoassay.

Properties for Fibrinogen

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms FGA, FGB, FGG
Presentation HRP
Reactivity Hu
Applications E, P, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Fibrinogen from Human plasma
Application Western blot: 1/1,000-1/5,000.
ELISA: 1/10,000-1/130,000.
Background Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.
The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
Caution Do Not add Sodium azide as preservative!
Concentration 1.0 mg/ml (by UV absorbance at 280 nm)
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Horseradish peroxidase
Delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer
Buffer System:
0.02 M Potassium phosphate, 0.15 M Sodium chloride, pH 7.2
0.01% (w/v) Gentamicin sulfate (Do NOT add Sodium azide!)
10 mg/ml BSA (immunoglobulin protease free)
Lyophilized purified Ig fraction
Restore with 0.1 ml of deionized water (or equivalent).
This product detects human Fibrinogen. Cross reactivity against Fibrinogen from other sources is unknown.
Immunoelectrophoresis give a single precipitin arc against anti-peroxidase, anti-goat serum as well as purified and partially purified Fibrinogen [human plasma].

Accessory Products

  • LinkedIn