TA319310 Fibrinogen antibody

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2 ml / €900.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Goat anti Human Fibrinogen


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  • TA319310

Product Description for Fibrinogen

Goat anti Human Fibrinogen.
Presentation: Serum
Product is tested for Enzyme Immunoassay, Immunoprecipitation, Western blot / Immunoblot, Paraffin Sections.

Properties for Fibrinogen

Product Category Primary Antibodies
Quantity 2 ml
Synonyms FGA, FGB, FGG
Presentation Serum
Reactivity Hu
Applications E, IP, P, WB
Clonality Polyclonal
Host Goat
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Fibrinogen from Human Plasma.
Application Suitable for Immunoblotting (Western or Dot blot), ELISA, Immunoprecipitation and most immunological methods requiring high titer and specificity.
Recommended Dilutions:
ELISA: 1/20,000-1/100,000.
Western Blot: 1/2,000-1/10,000.
Note: This product has been assayed against 1.0 µg of Fibrinogen [Human Plasma] in a standard sandwich ELISA using Peroxidase conjugated Affinity Purified anti-Goat IgG [H&L] (Rabbit) and (ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) as a substrate for 30 minutes at room temperature. A working dilution of 1/10,000 to 1/50,000 of the reconstitution concentration is suggested for this product.
Background Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.
The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
Concentration 90.0 mg/ml (by Refractometry)
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Multistep process.
Buffer System:
0.02M Potassium Phosphate, 0.15M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide as preservative, without stabilizers
Lyophilized purified IgG fraction
Restore with 1.0 ml of deionized water (or equivalent).
This antibody is prepared from monospecific antiserum by a delipidation and defibrination.
Assay by immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified Fibrinogen [Human Plasma].
Cross reactivity against Fibrinogen from other sources is unknown.

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