NB100-64932 Fibroblasts (Pan Reticular) antibody

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Rat anti Mouse Fibroblasts (Pan Reticular) ER-TR7


Product Description for Fibroblasts (Pan Reticular)

Rat anti Mouse Fibroblasts (Pan Reticular) ER-TR7.
Presentation: Purified
Product is tested for Frozen Sections, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections.

Properties for Fibroblasts (Pan Reticular)

Product Category Primary Antibodies
Quantity 0.125 mg
Synonyms Fibroblast Marker, Fibroblasten
Presentation Purified
Reactivity Ms
Applications C, F, ICC/IF, P
Clonality Monoclonal
Clone ER-TR7
Host Rat
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Isolated C3H thymic stromal cells
Isotype control SM15P, SM15PX
Application flow cytometry / FACS analysis, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen and Paraffin, Flow cytometry / FACS analysis, flow cytometry / FACS analysis , Immunohistochemistry-Paraffin 1:25, Immunohistochemistry-Frozen 1:50 - 1:100
Background Connective tissue consists of a ground of glycosaminoglycans, proteoglycans and glycoproteins through which various fibres run. These fibres can be collagenous, elastic or reticular. Reticular fibres are composed from the family of collagen proteins and give tensile strength. These fibres are made by reticular fibroblasts. This monoclonal antibody [ER-TR7] detects an antigen present in, and produced by, reticular fibroblasts. The antibody is useful to stain the microanatomy of various organs, in particular the connective tissue framework in lymphoid organs. The antibody also stains subendothelial deposits in the plaque area of atherosclerotic plaques.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
protein G purified
Buffer System:
0.09% Sodium Azide
protein G purified
NB100-64932 recognizes ER-TR7, an antigen that is located in the cytoplasm of reticular fibroblasts and is a component of the extracellular matrix of lymphoid and non-lymphoid organs. The antigen recognized by clone ER-TR7 has not been identified but studies suggest that it is likely to be distinct from laminin, fibronectin, collagen types I-IV, heparin sulphate proteoglycan, entactin and nidogen. Clone ER-TR7 has been used to stain the microanatomy of various organs and also stains subendothelial deposits in atherosclerotic plaques.

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