TA319623 Formin-like protein 1 (C-term) antibody

Rabbit Polyclonal FRL1 Antibody

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0.1 mg / €371.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Formin-like protein 1

TA319623

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  • TA319623

Product Description for Formin-like protein 1

Rabbit anti Human, Mouse, Rat Formin-like protein 1.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Formin-like protein 1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms C17orf1, C17orf1B, CLL-associated antigen KW-13, FMNL, FMNL1, Leukocyte formin
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Molecular weight 121 kDa
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
O95466
Immunogen:
A 16 amino acid peptide near the carboxy terminus of Human FRL1 (AP55523CP-N)
GeneID:
752
Property C-term
Add. information Blocking peptide available: blocking peptide (AP55523CP-N)
Application ELISA.
Western blot:
This antibody can be used for detection of FRL1 at 1-2 µg/ml. 
Positive Control: K562 cell lysate. v
Immunofluorescence: Start at 20 μg/ml.
Background The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
Concentration 1.0 mg/ml
General Readings Katoh M and Katoh M. Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico. Int. J. Oncol. 2003; 22:1161-8.
Yayoshi-Yamamoto S, Taniuchi I and Watanabe T. FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages. Mol. Cell. Biol. 2000; 20: 6872-81.
Favaro PM, Traina F, Vassallo J, et al. High expression of FMNL1 protein in T non-Hodgkin’s lymphomas. Leuk. Res. 2006; 30:735-8.
Gomez TS, Kumar K, Medeiros RB, et al. Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. Immunity 2007; 26:177-90.
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% Sodium Azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes  Formin-like protein 1 (C-term). Three alternatively spliced transcript variants have been observed.
Species:
Human, Mouse, Rat.

Accessory Products

Proteins and/or Positive Controls

Proteins for Formin-like protein 1 (5 products)

Catalog No. Species Pres. Purity   Source  

Formin-like protein 1

Formin-like protein 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Formin-like protein 1

Formin-like protein 1 Human Purified
  Abnova Taiwan Corp.

Formin-like protein 1

Formin-like protein 1 Human Purified
  Abnova Taiwan Corp.

Formin-like protein 1

Formin-like protein 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Formin-like protein 1

Formin-like protein 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Formin-like protein 1 (1 products)

Catalog No. Species Pres. Purity   Source  

FMNL1 293T Cell Transient Overexpression Lysate(Denatured)

FMNL1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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