AP20439PU-N FOXE3 / FKHL12 antibody

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0.1 mg / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat FOXE3 / FKHL12

AP20439PU-N

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  • AP20439PU-N

Product Description for FOXE3 / FKHL12

Rabbit anti Human, Mouse, Rat FOXE3 / FKHL12.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for FOXE3 / FKHL12

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms FREAC8, Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 33 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q13461
GeneID:
2301
Application Immunohistochemistry on Paraffin sections: 1/50-1/200.
Western Blot: 1/500-1/1000.
Background The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis.
Concentration 1.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography (> 95% (by SDS-PAGE)
Buffer System:
Phosphate buffered saline (PBS) with 0.05% Sodium azide, approx. pH 7.2.
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of FOXE3 protein.
(region surrounding Arg97)
Gene ID 2301

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