discontinued

AP00557PU-N FRA2 antibody

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0.5 mg / €480.00

Quick Overview

Rabbit anti Human FRA2

AP00557PU-N

Product Description for FRA2

Rabbit anti Human FRA2.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for FRA2

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms DP3062
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
A synthetic peptide derived from the C-terminus of human Fra2 protein.
Remarks:
Mol. Wt. of Antigen: 43 kDa
Application Western Blotting: Ab 5-10 µg/ml for 2hrs at RT. Recommended positive control: HeLa Cells.
Background Fos related antigen 2 (Fra2) belongs to the Fos family of nuclear oncogenes / transcription factors. Members from the Fos family of proteins undergo heterodimerization with Jun family of proteins through their leucine zippers to form activator protein-1 (AP-1) complex. This complex binds to TPA response element of several genesincluding interleukin- 2 and collagenase, which leads to their transcriptional activation.
Concentration 1 mg/ml
General Readings
  1. Hyder S M, et al. Critical reviews in Eukaryotic Gene expression 4: 55-116.
  2. Angel P and Karin M. (1991) Biochimica et Biophysica Acta 1072: 129-157.
Storage Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A chromatography
Buffer System:
10 mM PBS, pH 7.4, with 0.2 % BSA & 0.09 % sodium azide.
State:
Liquid IgG
Purified
Specificity
Specificity:
This antibody detects Fos related antigen 2.
Cellular Localization: Nuclear.
Species:
Human.

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