discontinued

NBP1-00831 FZD5/FZD8 antibody

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0.1 mg / €420.00

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Rabbit anti Human, Mouse, Rat FZD5/FZD8

Product Description for FZD5/FZD8

Rabbit anti Human, Mouse, Rat FZD5/FZD8.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for FZD5/FZD8

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Frizzled-5, Frizzled-8
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application ELISA, Western Blot, Western blot analysis of Frizzled-5/8 (W73) antibody in extracts from Jurkat cells. Detects a band at molecular weight: 75kDa, ELISA 1:5000-1:10000, Western Blot 1:500-1:1000,
Background The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
Frizzled-5/8 (W73) detects endogenous levels of Frizzled-5/8 protein.
Species:
Human, Mouse, Rat

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