AP51959PU-N Gastrin-releasing peptide receptor (Center) antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human Gastrin-releasing peptide receptor

AP51959PU-N

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Product Description for Gastrin-releasing peptide receptor

Rabbit anti Human Gastrin-releasing peptide receptor.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Paraffin Sections, Western blot / Immunoblot.

Properties for Gastrin-releasing peptide receptor

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms GRP-R, GRP-preferring bombesin receptor, GRPR
Presentation Aff - Purified
Reactivity Hu
Applications F, P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P30550
Immunogen:
KLH conjugated synthetic peptide between 130~160 amino acids from the Central region of Human Gastrin-releasing peptide receptor
GeneID:
2925
Property Center
Add. information Molecular Weight: 43199 Da
Application ELISA:  1/1000. 
Western Blot: 1/100-1/500. 
Flow Cytometry: 1/10-1/50. 
Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Background Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Concentration 0.45 mg/mL
General Readings Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
Chao, C., et al. J. Surg. Res. 156(1):26-31(2009)
Ananias, H.J., et al. Prostate 69(10):1101-1108(2009)
Fleischmann, A., et al. Endocr. Relat. Cancer 16(2):623-633(2009)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Protein A column, followed by peptide affinity purification
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human Gastrin-releasing peptide receptor (Center).
Gene ID 2925

Accessory Products

Proteins and/or Positive Controls

Proteins for Gastrin-releasing peptide receptor (4 products)

Catalog No. Species Pres. Purity   Source  

Gastrin-releasing peptide receptor

Gastrin-releasing peptide receptor Human
  Abnova Taiwan Corp.

Gastrin-releasing peptide receptor

Gastrin-releasing peptide receptor Human
  Abnova Taiwan Corp.

Gastrin-releasing peptide receptor

Gastrin-releasing peptide receptor Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Gastrin-releasing peptide receptor

Gastrin-releasing peptide receptor Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.
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