ARP54576_P050 GCLC antibody

See related secondary antibodies

Search for all "GCLC"

50 µg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Bovine, Canine, Human, Mouse, Rat, Zebrafish GCLC

ARP54576_P050

More Views

  • ARP54576_P050

Product Description for GCLC

Rabbit anti Bovine, Canine, Human, Mouse, Rat, Zebrafish GCLC.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for GCLC

Product Category Primary Antibodies
Quantity 50 µg
Synonyms GCS, GLCL, GLCLC
Presentation Aff - Purified
Reactivity Bov, Can, Hu, Ms, Rt, Ze
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
Q14TF0
GeneID:
2729
Add. information Rabbit Ig G is purified by peptide affinity chromatography method.
Application Suggested dilution at 1ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Background Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human GCLC with an internal ID of P31360
General Readings Jonsson,L.S., (2008) Int Arch Occup Environ Health 81 (7), 913-919
Format
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ?l of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20
State:
Aff - Purified
Gene ID 2729

Accessory Products

  • LinkedIn