NB100-78304 GCN5 antibody

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Rabbit anti Human, Mouse GCN5


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  • NB100-78304

Product Description for GCN5

Rabbit anti Human, Mouse GCN5.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for GCN5

Product Category Primary Antibodies
Quantity 0.2 ml
Presentation Aff - Purified
Reactivity Hu, Ms
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application immunofluorescence, Western Blot
Background GCN5 (general control of amino-acid synthesis 5) is a 94 kD member of the N-acetyltransferase superfamily. This nuclear protein is highly expressed in the liver where it functions as a transcriptional co-activator, transfering acetyl group from acetyl-CoA to epsilon amino acid of lysine 14 in core histone H3 to control chromatin remodeling during transcriptional activation. GCN5 is a component of the human STAGA transactivator complex (SPT3, TAF, and GCN5) and can be modified by phosphorylation (which inhibits activity). In addition to the STAGA complex proteins, GCN5 has been shown to interact with E1A and Myc. The Poly6072 antibody has been shown to be useful for Western blotting of human and mouse GCN5.
General Readings
  1. Poux, A., et al., 2002. PNAS 99:14065. 2. Candau, R., et al., 1996. Mol. Cell. Biol. 16:593. 3. Liu, X., et al., 2003. J. Biol. Chem. 278:20405.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and
Immunogen affinity purified
Aff - Purified
Mouse, Human.

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