NB110-89452 Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) antibody

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Mouse anti Human Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) 6G2F2


Product Description for Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b)

Mouse anti Human Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) 6G2F2.
Presentation: Ascites
Product is tested for Frozen Sections, Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b)

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms EC, EC=, GSK-3 alpha, GSK-3 beta, GSK3A, GSK3B, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase-3 beta
Presentation Ascites
Reactivity Hu
Applications C, E, P, WB
Clonality Monoclonal
Clone 6G2F2
Host Mouse
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Ni-NTA purified truncated recombinant GSK3 alpha expressed in E. Coli strain BL21 (DE3)
Application ELISA 1: 10000, Western Blot 1: 500- 1: 2000, Immunohistochemistry-Paraffin 1: 500- 1: 2000, Immunohistochemistry-Frozen 1: 500- 1: 2000,
Background GSK3 alpha (Glycogen synthase kinase 3 alpha), with 483-amino acid protein (about 53kDa), belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily,GSK3 subsubfamily, which also includes GSK3 beta.GSK3 is a multifunctional serine/threonine kinase that is usually inactivated by serine phosphorylation in response to extracellular cues. GSK3 is a key regulator of numerous signalling pathways, including cellular responses to Wnt, receptor tyrosine kinases and G-protein-coupled receptors and is involved in a wide range of cellular processes, ranging from glycogen metabolism to cell cycle regulation and proliferation.GSK3 alpha is implicated in the control of several regulatory proteins including glycogen synthase and transcription factors.
General Readings 1. Bradley W. Doble and James R. Woodgett
J. Cell Sci., Apr 2003; 116: 1175
2. C. Laura Sayas , Aafke Ariaens, Bas Ponsioen
Mol. Biol. Cell, Apr 2006; 17: 1834 ¨C 1844
Storage Store at 4C for short term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles.

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