discontinued

GTX14438 Guanylate Cyclase antibody

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50 µl / €440.00

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Rabbit anti Mouse, Rat Guanylate Cyclase

GTX14438

Product Description for Guanylate Cyclase

Rabbit anti Mouse, Rat Guanylate Cyclase.
Presentation: Serum
Product is tested for Western blot / Immunoblot.

Properties for Guanylate Cyclase

Product Category Primary Antibodies
Quantity 50 µl
Presentation Serum
Reactivity Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide: EFTEEEAKVPEIL, corresponding to amino acids 421-433 of Rat Guanylate Cyclase.
Application WB
Background Intestinal guanylate cyclase (GCC) is a transmembrane receptor expressed primarily in the intestine that regulates chloride secretion via the cystic fibrosis transmembrane conductance regulator. Binding of GCC to either the endogenous peptide guanylin or the bacterially derived heat stable enterotoxin STa, results in increased levels of cGMP and the stimulation of water and chloride secretion. In the case of exposure to STa, this leads to debilitating secretory diarrhea.
Concentration whole antiserum
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Whole antiserum
Buffer System:
Preservative: NoneConstituents: Whole Serum
Purity:
Whole antiserum
State:
Liquid
Serum
Specificity
Specificity:
Cross-reacts with Rat. Expected to cross-react with Mouse (92% identity with immunogen) due to sequence homology. Not yet tested in other species.

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