AP31149PU-N H/K/N-Ras (N-term) antibody

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50 µg / €470.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat H/K/N-Ras


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  • AP31149PU-N

Product Description for H/K/N-Ras

Rabbit anti Human, Mouse, Rat H/K/N-Ras.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for H/K/N-Ras

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Synthetic peptide - KLH conjugated
Antigen Modification: N-terminus.
Property N-term
Application ELISA: 1/20000.
Western Blot: 1/500-1/1000.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Background The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
Concentration 1.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Immunoaffinity Chromatography
Buffer System:
PBS (without Mg2+, Ca2+), pH 7.4 with 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse, Rat.
Species reactivity (tested):
This antibody detects endogenous levels of RASH/RASK protein.

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