AP26057PU-S H2B (41-45) antibody

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Rabbit anti Human, Mouse, Rat H2B

Product Description for H2B

Rabbit anti Human, Mouse, Rat H2B.
Properties: (41-45)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for H2B

Product Category Primary Antibodies
Quantity 50 µl
Synonyms GL105, H2BQ
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Peptide sequence around amino acids 41~45 derived from Human H2B
AA Sequence:
Property 41-45
Add. information Molecular Weight: 14 kDa
Application Western blot: 1/500-1/1000.
Incubate membrane with diluted antibody in 5% nonfat milk, 1xTBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Background Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Concentration 1.0 mg/ml
General Readings
  1. Borchert GM,et al. (2010) PLoS One.5(7):e11641.
  2. Pennini ME,et al.(2010) PLoS Pathog.6(7):e1000995.
  3. Lu C,et al. (2010) Sci China Life Sci.53(6):663-8.
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity Chromatography using epitope-specific peptide
Buffer System:
PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer
Liquid purified Ig fraction
Aff - Purified
This antibody detects endogenous level of total H2B protein.
Human, Mouse, Rat.
Gene ID 3018

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